2018 Swiss Open – Men's Singles

Main article: 2018 Swiss Open

An ATP player was the defending champion from 2017.

Seeds
🇪🇸 Rafael Nadal 🇷🇸 Novak Djokovic Roger Federer 🇦🇷 Juan Martín del Potro 🇩🇪 Alexander Zverev Marin Čilić 🇦🇹 Dominic Thiem Kevin Anderson 🇧🇬 Grigor Dimitrov 🇺🇸 John Isner 🇯🇵 Kei Nishikori Borna Ćorić